TRA2B

Across TCGA cell cohorts, TRA2B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,818 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRA2B-associated GO terms across cancer lineages are Regulation of DNA repair, Protein localization to chromosome, and Sister chromatid cohesion. Each is linked with TRA2B in more than 17 cancer types. Because this analysis shows association rather than direction, both TRA2B-to-partner and partner-to-TRA2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA repair grouped by TRA2B-low versus TRA2B-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRA2B→partner) and Y-score (partner→TRA2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of DNA repair →	+0.053	+0.723	<.001	.002	3	18
UPPER_AERODIGESTIVE_TRACT	Protein localization to chromosome →	+0.134	+1.136	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Sister chromatid cohesion →	+0.132	+1.309	<.001	<.001	3	17
SOFT_TISSUE	Double-strand break repair via homologous recombination →	+0.073	+0.607	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	DNA repair-dependent chromatin remodeling →	+0.121	+0.983	<.001	<.001	3	16
PANCREAS	Replication fork processing →	+0.111	+0.885	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,818 associations by consensus.

Regulation of DNA repair by TRA2B expression — PANCREAS

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