TRA2B

Across TCGA cell cohorts, TRA2B mutation is significantly associated with the drug of many other genes, with 24 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TRA2B-associated genes across cancer lineages are Mirin, CDK9_5038, and PAK_5339. Each is linked with TRA2B in more than 1 cancer types. Because this analysis shows association rather than direction, both TRA2B-to-partner and partner-to-TRA2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mirin grouped by TRA2B-low versus TRA2B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRA2B→partner) and Y-score (partner→TRA2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Mirin →	+0.424	+2.646	.025	.047	3	1
LARGE_INTESTINE	CDK9_5038 →	+0.550	+2.906	.047	.033	3	1
LARGE_INTESTINE	PAK_5339 →	+0.364	+2.649	.013	.046	3	1
LARGE_INTESTINE	50869 →	+0.450	+2.649	.033	.046	3	1
LARGE_INTESTINE	Zibotentan →	+0.213	+2.652	.036	.045	3	1
LARGE_INTESTINE	KIN001-236 →	+0.347	+2.652	.015	.045	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Mirin by TRA2B expression — LARGE_INTESTINE

Explore this box plot interactively →