TPTE2P5

Across TCGA patient cohorts, TPTE2P5 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TPTE2P5-associated genes across cancer lineages are RNU6-336P, MIR1225, and LDHAL6DP. Each is linked with TPTE2P5 in more than 1 cancer types. Because this analysis shows association rather than direction, both TPTE2P5-to-partner and partner-to-TPTE2P5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-336P grouped by TPTE2P5-low versus TPTE2P5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TPTE2P5→partner) and Y-score (partner→TPTE2P5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-336P →	+0.485	+4.852	<.001	.006	3	1
UCEC	MIR1225 →	+0.886	+5.027	<.001	.004	3	1
UCEC	LDHAL6DP →	+0.128	+4.694	.008	.007	3	1
UCEC	MIR5707 →	+0.710	+5.027	<.001	.004	3	1
UCEC	ATP6V1E1P2 →	+0.331	+4.661	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

RNU6-336P by TPTE2P5 expression — UCEC

Explore this box plot interactively →