Across TCGA pan-cancer cohorts, TPTE2P4 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of TPTE2P4’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where TPTE2P4 RNA is repressed in tumor relative to normal tissue. In most cancer types TPTE2P4 is over-expressed in tumor, although a few such as THCA and KIRP show the opposite, repressed pattern.

THCA and KIRP are the cancer types where TPTE2P4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TPTE2P4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	II,III,IV	−0.024	.005	5	view →
KIRP	Male	All	−0.011	.026	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: TPTE2P4 RNA expression & survival · all TPTE2P4 data types