TPT1

Across TCGA patient cohorts, TPT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,803 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TPT1-associated proteins across cancer lineages are COG3, ELF1, and CAVIN1. Each is linked with TPT1 in more than 5 cancer types. Because this analysis shows association rather than direction, both TPT1-to-partner and partner-to-TPT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TPT1 versus COG3 in OV, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TPT1→partner) and Y-score (partner→TPT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	COG3 →	+0.321	+0.759	<.001	<.001	3	6
UCEC	ELF1 →	+0.228	+0.507	<.001	.001	3	6
GBM	CAVIN1 →	+0.705	+0.510	<.001	<.001	3	5
BRCA	CAVIN3 →	+0.850	+0.511	<.001	<.001	3	5
BRCA	EHD2 →	+0.767	+0.601	<.001	<.001	3	5
BRCA	ESD →	+0.331	+0.480	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,803 associations by consensus.

TPT1 vs COG3 — OV

Explore this scatter interactively →