TPST2

Across TCGA cell cohorts, TPST2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,837 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TPST2-associated GO terms across cancer lineages are Protein sulfation, Viral process, and Caveolin-mediated endocytosis. Each is linked with TPST2 in more than 19 cancer types. Because this analysis shows association rather than direction, both TPST2-to-partner and partner-to-TPST2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein sulfation grouped by TPST2-low versus TPST2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TPST2→partner) and Y-score (partner→TPST2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Protein sulfation →	+1.618	+2.048	<.001	<.001	3	20
STOMACH	Viral process →	+0.091	+1.079	<.001	.007	2	14
OVARY	Caveolin-mediated endocytosis →	+0.166	+1.052	<.001	<.001	3	12
SKIN	Retrograde transport, endosome to Golgi →	+0.057	+0.909	.002	<.001	2	12
BONE	Cytosolic transport →	+0.073	+1.763	.006	.003	3	11
BLOOD_Lymphoma	Protein localization to microtubule plus-end →	+0.211	+1.110	.003	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,837 associations by consensus.

Protein sulfation by TPST2 expression — BREAST

Explore this box plot interactively →