TPRG1-AS2

Across TCGA pan-cancer cohorts, TPRG1-AS2 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated TPRG1-AS2 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher TPRG1-AS2 RNA is associated with better overall survival. In most high-consensus cancer types, elevated TPRG1-AS2 expression acts as an unfavorable survival marker, although some lineages such as BRCA and HNSC show a favorable association.

BRCA, KIRC, and HNSC are the cancer types where TPRG1-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.974	0.949	<.001	94	view →
KIRC	OS	Quartile	All	0.528	0.669	<.001	93	view →
HNSC	OS	Quartile	IV	0.839	0.657	.002	46	view →
DLBC	DFS	Tertile	All	0.202	0.757	.001	33	view →
OV	OS	Tertile	IV	0.566	0.859	.005	28	view →
MESO	DFS	Tertile	All	0.287	0.166	.021	26	view →
UCEC	DFS	Tertile	All	0.483	0.673	.001	24	view →
LGG	OS	Tertile	All	0.732	0.902	.001	24	view →
CHOL	DFS	Tertile	All	0.113	0.594	<.001	24	view →
ESCA	DFS	Tertile	III,IV	0.582	0.274	.002	21	view →
READ	DFS	Tertile	IV	0.255	0.628	.020	18	view →
TGCT	DFS	Tertile	II,III,IV	0.621	0.949	.034	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

TPRG1-AS2–BRCA (OS)

Open the BRCA breakdown →