TPRG1-AS2

Across TCGA pan-cancer cohorts, TPRG1-AS2 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of TPRG1-AS2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TPRG1-AS2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TPRG1-AS2 is over-expressed in tumor.

KIRC, BRCA, and KICH are the cancer types where TPRG1-AS2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TPRG1-AS2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.063	<.001	11	view →
BRCA	Female	All	+0.313	<.001	6	view →
KICH	All	All	+0.096	.002	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

TPRG1-AS2–KIRC

Open the KIRC breakdown →