TPRG1-AS1

Across TCGA pan-cancer cohorts, TPRG1-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated TPRG1-AS1 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher TPRG1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TPRG1-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and LIHC show a favorable association.

BLCA, LGG, and BRCA are the cancer types where TPRG1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	All	0.415	0.574	<.001	78	view →
LGG	OS	Median	All	0.725	0.899	<.001	50	view →
BRCA	DFS	Median	All	0.968	0.929	<.001	44	view →
LIHC	OS	Median	II,III,IV	0.562	0.301	<.001	34	view →
UCS	DFS	Median	III,IV	0.513	0.156	.008	32	view →
SKCM	DFS	Tertile	All	0.288	0.141	.001	25	view →
KIRC	DFS	Quartile	All	0.865	0.656	<.001	24	view →
GBM	DFS	Tertile	All	0.216	0.415	.009	18	view →
READ	DFS	Tertile	III,IV	0.498	0.190	.011	18	view →
ACC	DFS	Quartile	All	0.213	0.686	.005	15	view →
STAD	OS	Tertile	II,III,IV	0.390	0.668	.016	13	view →
LAML	DFS	Median	All	0.261	0.524	.006	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

TPRG1-AS1–BLCA (DFS)

Open the BLCA breakdown →