TPRA1

Across TCGA cell cohorts, TPRA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,067 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TPRA1-associated GO terms across cancer lineages are Intracellular receptor signaling pathway, Positive regulation of intracellular transport, and Positive regulation of response to cytokine stimulus. Each is linked with TPRA1 in more than 12 cancer types. Because this analysis shows association rather than direction, both TPRA1-to-partner and partner-to-TPRA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intracellular receptor signaling pathway grouped by TPRA1-low versus TPRA1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TPRA1→partner) and Y-score (partner→TPRA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Intracellular receptor signaling pathway →	+0.052	+1.024	<.001	.003	3	13
SOFT_TISSUE	Positive regulation of intracellular transport →	+0.071	+0.842	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Positive regulation of response to cytokine stimulus →	+0.104	+0.662	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Regulation of cytokine-mediated signaling pathway →	+0.069	+0.671	<.001	<.001	3	12
BONE	Actomyosin contractile ring assembly actin filament organization →	+0.322	+1.130	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Positive regulation of autophagy →	+0.073	+0.870	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,067 associations by consensus.

Intracellular receptor signaling pathway by TPRA1 expression — BONE

Explore this box plot interactively →