TPM1-AS

Across TCGA pan-cancer cohorts, TPM1-AS RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated TPM1-AS data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher TPM1-AS RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated TPM1-AS expression acts as an unfavorable survival marker, although some lineages such as ACC and READ show a favorable association.

ACC, LUSC, and MESO are the cancer types where TPM1-AS RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.621	0.299	<.001	117	view →
LUSC	DFS	Quartile	II,III,IV	0.259	0.548	<.001	58	view →
MESO	OS	Tertile	All	0.249	0.507	.001	51	view →
READ	OS	Tertile	II,III,IV	0.804	0.287	.005	42	view →
SKCM	OS	Median	II,III,IV	0.508	0.224	.006	38	view →
CESC	DFS	Median	All	0.763	0.875	.001	30	view →
COAD	OS	Tertile	III,IV	0.694	0.902	.008	22	view →
UCEC	OS	Tertile	All	0.815	0.900	.005	20	view →
BLCA	OS	Tertile	III,IV	0.435	0.696	.007	19	view →
THCA	DFS	Median	All	0.899	0.761	<.001	12	view →
THYM	DFS	Tertile	All	1.000	0.711	.011	12	view →
KIRP	DFS	Tertile	All	1.000	0.771	.012	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

TPM1-AS–ACC (DFS)

Open the ACC breakdown →