Across TCGA patient cohorts, TP73-AS1 mutation is significantly associated with the RNA expression of many other genes, with 83 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TP73-AS1-associated genes across cancer lineages are CDYLP1, ZNF90P2, and CRLF3P1. Each is linked with TP73-AS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TP73-AS1-to-partner and partner-to-TP73-AS1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TP73-AS1→partner) and Y-score (partner→TP73-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	CDYLP1 →	+0.061	+5.653	<.001	.003	3	1
READ	ZNF90P2 →	+0.047	+5.925	<.001	.002	3	1
READ	CRLF3P1 →	+0.069	+5.653	<.001	.003	3	1
READ	KIR2DP1 →	+0.074	+5.925	<.001	.002	3	1
READ	UGT2B24P →	+0.097	+5.219	<.001	.006	3	1
READ	MIR3688-1 →	+0.423	+5.653	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 83 associations by consensus.

Exploration

TP73-AS1 survival (RNA) · tumor vs normal (RNA) · all TP73-AS1 data types