TP63

Across TCGA cell cohorts, TP63 RNA expression is significantly associated with the RNA expression of many other genes, with 4,676 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible TP63-associated genes across cancer lineages are TPRG1, KRT6A, and CSTA. Each is linked with TP63 in more than 8 cancer types. Because this analysis shows association rather than direction, both TP63-to-partner and partner-to-TP63 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TP63 versus TPRG1 in LUNG_NSCLC_LUSC, with a Pearson correlation of 0.85.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TP63→partner) and Y-score (partner→TP63) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	TPRG1 →	+4.059	+6.315	<.001	<.001	3	9
OESOPHAGUS	KRT6A →	+6.636	+3.792	<.001	<.001	3	8
URINARY_TRACT	CSTA →	+5.296	+4.931	<.001	<.001	3	7
URINARY_TRACT	BLCAP →	+1.807	+3.611	<.001	<.001	3	7
BLOOD_Lymphoma	RXRA →	+1.603	+2.249	<.001	<.001	3	7
URINARY_TRACT	S100A2 →	+5.248	+3.574	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,676 associations by consensus.

TP63 vs TPRG1 — LUNG_NSCLC_LUSC

Explore this scatter interactively →