TP53TG5

Across TCGA cell cohorts, TP53TG5 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TP53TG5-associated genes across cancer lineages are OR6N1, GAGE12G, and KIR2DL3. Each is linked with TP53TG5 in more than 1 cancer types. Because this analysis shows association rather than direction, both TP53TG5-to-partner and partner-to-TP53TG5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6N1 grouped by TP53TG5-low versus TP53TG5-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TP53TG5→partner) and Y-score (partner→TP53TG5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR6N1 →	+0.257	+5.415	<.001	.004	3	1
SKIN	GAGE12G →	+0.368	+4.977	<.001	.007	3	1
SKIN	KIR2DL3 →	+0.006	+4.977	<.001	.007	3	1
SKIN	CLRN2 →	+0.025	+4.977	<.001	.007	3	1
LARGE_INTESTINE	CD300H →	+0.033	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

OR6N1 by TP53TG5 expression — SKIN

Explore this box plot interactively →