TP53TG3GP

Across TCGA pan-cancer cohorts, TP53TG3GP RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated TP53TG3GP data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher TP53TG3GP RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TP53TG3GP expression acts as an unfavorable survival marker, although some lineages such as ESCA and UCS show a favorable association.

KICH, LUSC, and ESCA are the cancer types where TP53TG3GP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
LUSC	OS	Tertile	II,III,IV	0.195	0.588	.005	44	view →
ESCA	DFS	Tertile	IV	0.826	0.284	.034	36	view →
STAD	DFS	Tertile	All	0.462	0.732	.006	27	view →
UCS	DFS	Tertile	II,III,IV	0.675	0.315	.006	22	view →
PAAD	DFS	Tertile	II,III,IV	0.682	0.256	.034	18	view →
CHOL	OS	Tertile	All	0.089	0.673	.018	18	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	18	view →
LUAD	OS	Tertile	II,III,IV	0.480	0.693	.032	15	view →
SKCM	DFS	Tertile	III,IV	0.316	0.568	.048	6	view →
LIHC	OS	Tertile	All	0.616	0.794	.025	6	view →
OV	OS	Tertile	IV	1.000	0.714	.044	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

TP53TG3GP–KICH (DFS)

Open the KICH breakdown →