TP53I13

Across TCGA patient cohorts, TP53I13 mutation is significantly associated with the RNA expression of many other genes, with 311 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TP53I13-associated genes across cancer lineages are RN7SL538P, GTF2IP22, and RNU5F-6P. Each is linked with TP53I13 in more than 1 cancer types. Because this analysis shows association rather than direction, both TP53I13-to-partner and partner-to-TP53I13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL538P grouped by TP53I13-low versus TP53I13-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TP53I13→partner) and Y-score (partner→TP53I13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL538P →	+0.106	+3.923	<.001	.003	3	2
UCEC	GTF2IP22 →	+0.331	+3.036	<.001	.009	3	2
BRCA	RNU5F-6P →	+0.268	+7.731	<.001	.009	3	2
BRCA	RNY1P8 →	+0.270	+7.731	<.001	.009	3	2
BRCA	MIR3118-3 →	+0.558	+8.471	<.001	.005	3	1
LUAD	RNA5SP204 →	+0.789	+7.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 311 associations by consensus.

RN7SL538P by TP53I13 expression — SKCM

Explore this box plot interactively →