TP53I13

Across TCGA pan-cancer cohorts, TP53I13 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated TP53I13 data layer compared with 4 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher TP53I13 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TP53I13 expression acts as an unfavorable survival marker, although some lineages such as UCEC and PAAD show a favorable association.

KIRC, UCEC, and UVM are the cancer types where TP53I13 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.551	0.721	<.001	134	view →
UCEC	DFS	Quartile	All	0.842	0.613	.001	78	view →
UVM	OS	Tertile	All	0.362	0.651	.002	62	view →
LGG	DFS	Median	All	0.585	0.878	<.001	54	view →
PAAD	OS	Median	All	0.540	0.255	<.001	37	view →
HNSC	OS	Median	All	0.290	0.496	.008	17	view →
READ	DFS	Median	All	0.842	0.610	.019	15	view →
MESO	DFS	Median	II,III,IV	0.304	0.442	.016	13	view →
COAD	DFS	Quartile	All	0.747	0.846	.028	11	view →
OV	OS	Quartile	All	0.797	0.898	.008	10	view →
CHOL	DFS	Median	III,IV	0.647	0.127	.006	9	view →
LIHC	OS	Quartile	All	0.695	0.865	.008	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

TP53I13–KIRC (DFS)

Open the KIRC breakdown →