TP53I13

Across TCGA patient cohorts, TP53I13 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TP53I13-associated genes across cancer lineages are CD8+ Tcm, lymphatic Endothelial cells, and pDC. Each is linked with TP53I13 in more than 1 cancer types. Because this analysis shows association rather than direction, both TP53I13-to-partner and partner-to-TP53I13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ Tcm grouped by TP53I13-low versus TP53I13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TP53I13→partner) and Y-score (partner→TP53I13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ Tcm →	+0.025	+2.350	.010	.031	3	1
UCEC	lymphatic Endothelial cells →	-0.025	-3.138	.035	.019	3	1
UCEC	pDC →	+0.061	+3.177	.013	.010	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CD8+ Tcm by TP53I13 expression — UCEC

Explore this box plot interactively →