TP53I13

Across TCGA cell cohorts, TP53I13 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TP53I13-associated genes across cancer lineages are IQCF5 and OC90. Each is linked with TP53I13 in more than 1 cancer types. Because this analysis shows association rather than direction, both TP53I13-to-partner and partner-to-TP53I13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IQCF5 grouped by TP53I13-low versus TP53I13-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TP53I13→partner) and Y-score (partner→TP53I13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	IQCF5 →	+0.104	+5.201	<.001	.006	3	1
BLOOD_Leukemia	OC90 →	+0.013	+5.201	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

IQCF5 by TP53I13 expression — BLOOD_Leukemia

Explore this box plot interactively →