Across TCGA patient cohorts, TOR4A mutation is significantly associated with the RNA expression of many other genes, with 1,191 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TOR4A-associated genes across cancer lineages are RNU6-40P, RNA5SP293, and VN1R92P. Each is linked with TOR4A in more than 1 cancer types. Because this analysis shows association rather than direction, both TOR4A-to-partner and partner-to-TOR4A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TOR4A→partner) and Y-score (partner→TOR4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-40P →	+0.132	+3.984	<.001	.009	3	2
CESC	RNA5SP293 →	+0.148	+5.000	<.001	.001	3	2
CESC	VN1R92P →	+0.020	+3.984	<.001	.009	3	2
UCEC	IGHD1-1 →	+0.315	+2.920	.002	.008	3	2
UCEC	KLHL18 →	+0.490	+2.831	<.001	.001	3	2
UCEC	KIF1C →	+0.465	+3.483	.003	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,191 associations by consensus.

Exploration

TOR4A survival (RNA) · tumor vs normal (RNA) · all TOR4A data types