TOR3A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TOR3A mutation is significantly associated with the RNA expression of many other genes, with 239 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TOR3A-associated genes across cancer lineages are RN7SL51P, RN7SL420P, and RNU6-1137P. Each is linked with TOR3A in more than 1 cancer types. Because this analysis shows association rather than direction, both TOR3A-to-partner and partner-to-TOR3A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TOR3A→partner) and Y-score (partner→TOR3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMRN7SL51P →+0.195+5.159<.001.00732
SKCMRN7SL420P →+0.160+5.771<.001.00332
COADRNU6-1137P →+0.402+5.392<.001.00232
UCECMIR3927 →+0.130+4.010<.001.00732
SKCMRPS21P8 →+0.198+6.469<.001.00132
SKCMLINC01831 →+0.167+5.159<.001.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 239 associations by consensus.

Exploration