TOR2A

Across TCGA cell cohorts, TOR2A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,880 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TOR2A-associated GO terms across cancer lineages are Vasopressin secretion, CTP salvage, and Transcription pausing by RNA polymerase II. Each is linked with TOR2A in more than 19 cancer types. Because this analysis shows association rather than direction, both TOR2A-to-partner and partner-to-TOR2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vasopressin secretion grouped by TOR2A-low versus TOR2A-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TOR2A→partner) and Y-score (partner→TOR2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Vasopressin secretion →	+1.387	+1.438	<.001	<.001	3	20
BONE	CTP salvage →	+0.162	+0.963	<.001	<.001	3	13
BLOOD_Lymphoma	Transcription pausing by RNA polymerase II →	+0.144	+0.797	<.001	<.001	3	13
LIVER	Regulation of chromatin organization →	+0.088	+0.626	.001	.007	2	13
PANCREAS	Dolichol phosphate mannose biosynthetic process →	+0.132	+0.827	.001	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.124	+0.791	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,880 associations by consensus.

Vasopressin secretion by TOR2A expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →