TONSL-AS1

Across TCGA patient cohorts, TONSL-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,215 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TONSL-AS1-associated proteins across cancer lineages are SF3B3, MSH6, and ATAD2. Each is linked with TONSL-AS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both TONSL-AS1-to-partner and partner-to-TONSL-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TONSL-AS1 versus SF3B3 in GBM, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TONSL-AS1→partner) and Y-score (partner→TONSL-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SF3B3 →	+0.252	+0.476	.001	.001	3	6
GBM	MSH6 →	+0.483	+0.442	.002	.004	2	7
LSCC	ATAD2 →	+0.531	+0.594	<.001	<.001	3	6
LSCC	DDX27 →	+0.304	+0.518	.009	.002	3	5
LSCC	VIRMA →	+0.265	+0.684	<.001	<.001	3	5
UCEC	KIF2C →	+0.680	+0.601	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,215 associations by consensus.

TONSL-AS1 vs SF3B3 — GBM

Explore this scatter interactively →