TOMM40

Across TCGA cell cohorts, TOMM40 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,162 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TOMM40-associated GO terms across cancer lineages are rRNA metabolic process, Maturation of SSU-rRNA, and Nucleolar large rRNA transcription by RNA polymerase I. Each is linked with TOMM40 in more than 18 cancer types. Because this analysis shows association rather than direction, both TOMM40-to-partner and partner-to-TOMM40 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, rRNA metabolic process grouped by TOMM40-low versus TOMM40-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TOMM40→partner) and Y-score (partner→TOMM40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	rRNA metabolic process →	+0.105	+0.806	.003	.008	3	19
LUNG_SCLC	Maturation of SSU-rRNA →	+0.131	+0.742	<.001	<.001	3	19
OESOPHAGUS	Nucleolar large rRNA transcription by RNA polymerase I →	+0.124	+0.799	.005	.002	3	19
LUNG_NSCLC_LUSC	Transcription initiation at RNA polymerase I promoter →	+0.102	+0.749	.009	<.001	3	19
BLOOD_Lymphoma	Ribosome biogenesis →	+0.098	+1.257	<.001	<.001	3	18
BONE	rRNA processing →	+0.106	+0.797	.005	.008	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,162 associations by consensus.

rRNA metabolic process by TOMM40 expression — BONE

Explore this box plot interactively →