TOMM22P4

Across TCGA pan-cancer cohorts, TOMM22P4 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated TOMM22P4 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TOMM22P4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TOMM22P4 expression acts as an unfavorable survival marker, although some lineages such as ESCA and SKCM show a favorable association.

HNSC, STAD, and LIHC are the cancer types where TOMM22P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.282	0.693	<.001	96	view →
STAD	DFS	Tertile	All	0.273	0.731	<.001	60	view →
LIHC	OS	Tertile	All	0.059	0.775	<.001	60	view →
UCS	DFS	Tertile	All	0.140	0.538	<.001	54	view →
UCEC	DFS	Tertile	III,IV	0.670	0.802	.033	30	view →
SARC	OS	Tertile	All	0.235	0.734	.004	27	view →
BLCA	DFS	Tertile	III,IV	0.169	0.445	.017	18	view →
ESCA	OS	Tertile	III,IV	1.000	0.374	.043	12	view →
THYM	DFS	Tertile	II,III,IV	0.091	0.842	.001	9	view →
SKCM	DFS	Tertile	II,III,IV	0.792	0.558	.036	9	view →
COAD	DFS	Tertile	All	0.108	0.556	.032	9	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

TOMM22P4–HNSC (OS)

Open the HNSC breakdown →