TOMM22P4

Across TCGA pan-cancer cohorts, TOMM22P4 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of TOMM22P4’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where TOMM22P4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TOMM22P4 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

BRCA and THCA are the cancer types where TOMM22P4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TOMM22P4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	II,III,IV	+0.061	.033	4	view →
THCA	All	All	−0.034	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

TOMM22P4–BRCA

Open the BRCA breakdown →