TOMM22

Across TCGA cell cohorts, TOMM22 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,663 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TOMM22-associated GO terms across cancer lineages are DNA replication initiation, Positive regulation of mitochondrial fusion, and Maturation of SSU-rRNA. Each is linked with TOMM22 in more than 15 cancer types. Because this analysis shows association rather than direction, both TOMM22-to-partner and partner-to-TOMM22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by TOMM22-low versus TOMM22-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TOMM22→partner) and Y-score (partner→TOMM22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	DNA replication initiation →	+0.178	+0.617	<.001	<.001	3	16
PANCREAS	Positive regulation of mitochondrial fusion →	+0.191	+0.755	<.001	<.001	3	15
BONE	Maturation of SSU-rRNA →	+0.140	+0.584	<.001	.001	3	14
BONE	Ribosomal large subunit biogenesis →	+0.116	+0.487	.005	.006	3	14
BONE	DNA-templated DNA replication →	+0.130	+0.471	.009	.002	3	14
BONE	Mitotic DNA replication checkpoint signaling →	+0.156	+0.473	.008	.003	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,663 associations by consensus.

DNA replication initiation by TOMM22 expression — SOFT_TISSUE

Explore this box plot interactively →