TOMM20P2

Across TCGA pan-cancer cohorts, TOMM20P2 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated TOMM20P2 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher TOMM20P2 RNA is associated with better overall survival. In most high-consensus cancer types, elevated TOMM20P2 expression acts as an unfavorable survival marker, although some lineages such as SKCM and HNSC show a favorable association.

SKCM, HNSC, and OV are the cancer types where TOMM20P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	All	0.412	0.266	<.001	141	view →
HNSC	DFS	Median	All	0.667	0.535	<.001	124	view →
OV	DFS	Quartile	All	0.262	0.145	.004	56	view →
LGG	DFS	Median	All	0.785	0.871	<.001	46	view →
KIRP	DFS	Quartile	All	0.515	0.824	<.001	36	view →
LUAD	DFS	Quartile	All	0.891	0.743	.007	33	view →
ESCA	DFS	Median	III,IV	0.579	0.288	<.001	27	view →
BLCA	OS	Median	IV	0.393	0.187	.011	21	view →
SARC	OS	Tertile	All	0.664	0.345	<.001	20	view →
UCEC	OS	Tertile	IV	0.671	0.230	.005	20	view →
KIRC	DFS	Tertile	III,IV	0.497	0.217	.011	18	view →
CHOL	OS	Tertile	All	0.754	0.267	.013	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

TOMM20P2–SKCM (OS)

Open the SKCM breakdown →