TOMM20P2

Across TCGA pan-cancer cohorts, TOMM20P2 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of TOMM20P2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TOMM20P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TOMM20P2 is over-expressed in tumor, although a few such as LUSC and THCA show the opposite, repressed pattern.

KIRC, LUSC, and STAD are the cancer types where TOMM20P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TOMM20P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	IV	+1.045	<.001	10	view →
LUSC	All	II,III,IV	−0.608	<.001	7	view →
STAD	All	All	+0.660	.006	5	view →
THCA	Female	All	−0.388	.007	5	view →
HNSC	All	IV	+0.317	.005	4	view →
KICH	All	All	−0.240	.007	3	view →
BRCA	All	III,IV	−0.443	.012	2	view →
UCEC	All	All	−0.382	.006	2	view →
BLCA	Male	IV	+0.607	.047	1	view →
KIRP	Female	All	+0.274	.030	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

TOMM20P2–KIRC

Open the KIRC breakdown →