Across TCGA pan-cancer cohorts, TOMM20L Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated TOMM20L data layer compared with 27 for mass-spec protein.

The strongest signal is observed in thyroid carcinoma (THCA), where higher TOMM20L Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TOMM20L expression acts as an unfavorable survival marker.

THCA are the cancer types where TOMM20L Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Median	All	0.342	0.955	<.001	3	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: TOMM20L tumor-vs-normal RNA expression · all TOMM20L data types