TOMM20

Across TCGA patient cohorts, TOMM20 protein abundance is significantly associated with the RNA expression of many other genes, with 11,043 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TOMM20-associated genes across cancer lineages are TCTEX1D4, C22orf34, and PLA2G5. Each is linked with TOMM20 in more than 3 cancer types. Because this analysis shows association rather than direction, both TOMM20-to-partner and partner-to-TOMM20 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TOMM20 versus TCTEX1D4 in LSCC, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TOMM20→partner) and Y-score (partner→TOMM20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TCTEX1D4 →	-0.562	-0.489	<.001	<.001	3	4
HNSC	C22orf34 →	-0.726	-0.435	<.001	.002	3	4
LSCC	PLA2G5 →	-0.575	-0.449	<.001	<.001	3	4
UCEC	CNN1 →	-1.562	-0.320	<.001	<.001	3	4
UCEC	FGF7 →	-0.952	-0.381	.001	<.001	3	4
UCEC	SPARCL1 →	-1.245	-0.332	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,043 associations by consensus.

TOMM20 vs TCTEX1D4 — LSCC

Explore this scatter interactively →