TOM1L2

Across TCGA pan-cancer cohorts, TOM1L2 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TOM1L2 data layer compared with 26 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher TOM1L2 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TOM1L2 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

KIRC, UCEC, and BLCA are the cancer types where TOM1L2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.266	0.805	.017	12	view →
UCEC	DFS	Median	All	0.965	0.623	.011	10	view →
BLCA	OS	Median	All	0.188	0.687	.020	6	view →
COAD	OS	Median	All	0.556	0.870	.024	6	view →
SKCM	OS	Median	All	0.368	0.784	.015	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TOM1L2–KIRC (OS)

Open the KIRC breakdown →