TOM1L2

Across TCGA cell cohorts, TOM1L2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TOM1L2-associated genes across cancer lineages are FAM205A, GSG1L2, and CFHR1. Each is linked with TOM1L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TOM1L2-to-partner and partner-to-TOM1L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM205A grouped by TOM1L2-low versus TOM1L2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TOM1L2→partner) and Y-score (partner→TOM1L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FAM205A →	+0.020	+4.029	<.001	.001	3	1
LARGE_INTESTINE	GSG1L2 →	+0.011	+3.700	<.001	.009	3	1
LARGE_INTESTINE	CFHR1 →	+0.091	+3.333	.008	.009	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

FAM205A by TOM1L2 expression — LARGE_INTESTINE

Explore this box plot interactively →