TOM1

Across TCGA patient cohorts, TOM1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,430 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TOM1-associated proteins across cancer lineages are TOM1_S376, NNMT, and TOM1_S160. Each is linked with TOM1 in more than 5 cancer types. Because this analysis shows association rather than direction, both TOM1-to-partner and partner-to-TOM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TOM1 versus TOM1_S376 in UCEC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TOM1→partner) and Y-score (partner→TOM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TOM1_S376 →	+0.650	+0.669	<.001	.001	3	6
OV	NNMT →	+0.809	+0.528	<.001	<.001	3	6
PDAC	TOM1_S160 →	+0.830	+0.452	<.001	<.001	3	5
UCEC	CTSB →	+0.464	+0.722	.001	.005	3	5
GBM	PDS5B →	-0.279	-0.243	.003	.009	3	5
LSCC	TCERG1 →	-0.182	-0.284	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,430 associations by consensus.

TOM1 vs TOM1_S376 — UCEC

Explore this scatter interactively →