TOM1

Across TCGA patient cohorts, TOM1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,730 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TOM1-associated genes across cancer lineages are ARFGAP3, IL1R1, and LINC01094. Each is linked with TOM1 in more than 6 cancer types. Because this analysis shows association rather than direction, both TOM1-to-partner and partner-to-TOM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TOM1 versus ARFGAP3 in UCEC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TOM1→partner) and Y-score (partner→TOM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ARFGAP3 →	+0.766	+0.239	<.001	<.001	3	7
LSCC	IL1R1 →	+0.876	+0.251	<.001	<.001	3	6
GBM	LINC01094 →	+0.863	+0.248	<.001	<.001	3	6
GBM	ATP8B4 →	+0.605	+0.170	.001	.007	3	5
COAD	PDGFRL →	+0.965	+0.193	<.001	<.001	3	5
GBM	LIG1 →	-0.762	-0.267	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,730 associations by consensus.

TOM1 vs ARFGAP3 — UCEC

Explore this scatter interactively →