TOLLIP-AS1

Across TCGA patient cohorts, TOLLIP-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,144 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TOLLIP-AS1-associated proteins across cancer lineages are PLAU, RPS6, and HK3. Each is linked with TOLLIP-AS1 in more than 3 cancer types. Because this analysis shows association rather than direction, both TOLLIP-AS1-to-partner and partner-to-TOLLIP-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TOLLIP-AS1 versus PLAU in OV, with a Pearson correlation of -0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TOLLIP-AS1→partner) and Y-score (partner→TOLLIP-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PLAU →	-0.619	-0.643	.006	.003	3	4
GBM	RPS6 →	-0.333	-0.336	.001	.003	3	4
GBM	HK3 →	-0.746	-0.425	.005	.007	3	4
BRCA	EPM2AIP1 →	+0.320	+0.595	<.001	<.001	3	4
BRCA	ISG20 →	-0.622	-0.555	<.001	.005	3	4
OV	TCEAL4 →	+0.450	+0.541	<.001	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,144 associations by consensus.

TOLLIP-AS1 vs PLAU — OV

Explore this scatter interactively →