TNS4

Across TCGA patient cohorts, TNS4 mutation is significantly associated with the RNA expression of many other genes, with 1,597 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TNS4-associated genes across cancer lineages are MIR511, BAG3, and MAMDC4. Each is linked with TNS4 in more than 2 cancer types. Because this analysis shows association rather than direction, both TNS4-to-partner and partner-to-TNS4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR511 grouped by TNS4-low versus TNS4-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNS4→partner) and Y-score (partner→TNS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR511 →	+0.068	+3.163	<.001	.003	3	3
UCEC	BAG3 →	+0.602	+2.502	<.001	.001	3	3
UCEC	MAMDC4 →	+0.606	+3.716	.001	<.001	3	3
OV	MIR885 →	+0.512	+5.137	<.001	.007	3	2
OV	PABPC1L2B-AS1 →	+0.023	+5.215	.003	.007	3	2
OV	MTCO1P35 →	+0.216	+5.475	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,597 associations by consensus.

MIR511 by TNS4 expression — SKCM

Explore this box plot interactively →