TNRC6B

Across TCGA patient cohorts, TNRC6B RNA expression is significantly associated with the protein abundance of many other proteins, with 16,680 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TNRC6B-associated proteins across cancer lineages are XRCC6, RPL26, and GTPBP1. Each is linked with TNRC6B in more than 5 cancer types. Because this analysis shows association rather than direction, both TNRC6B-to-partner and partner-to-TNRC6B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNRC6B versus XRCC6 in GBM, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TNRC6B→partner) and Y-score (partner→TNRC6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	XRCC6 →	+0.243	+0.415	<.001	<.001	3	6
GBM	RPL26 →	-0.755	-0.623	.008	.007	3	5
GBM	GTPBP1 →	+0.287	+0.516	<.001	<.001	3	5
GBM	ST13 →	+0.349	+0.539	<.001	<.001	3	5
BRCA	RPL5 →	-0.201	-0.391	<.001	<.001	3	5
GBM	SETMAR →	+0.399	+0.380	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,680 associations by consensus.

TNRC6B vs XRCC6 — GBM

Explore this scatter interactively →