TNRC6B

Across TCGA cell cohorts, TNRC6B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,991 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TNRC6B-associated GO terms across cancer lineages are Negative regulation of chromosome condensation, Positive regulation of T-helper 17 cell lineage commitment, and Nucleic acid transport. Each is linked with TNRC6B in more than 18 cancer types. Because this analysis shows association rather than direction, both TNRC6B-to-partner and partner-to-TNRC6B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of chromosome condensation grouped by TNRC6B-low versus TNRC6B-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNRC6B→partner) and Y-score (partner→TNRC6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Negative regulation of chromosome condensation →	+0.171	+1.089	<.001	<.001	3	19
OESOPHAGUS	Positive regulation of T-helper 17 cell lineage commitment →	+0.273	+1.155	.002	.002	3	18
OESOPHAGUS	Nucleic acid transport →	+0.123	+0.885	<.001	.001	3	18
OESOPHAGUS	RNA transport →	+0.123	+0.885	<.001	.001	3	18
OESOPHAGUS	Nuclear export →	+0.113	+0.997	<.001	<.001	3	18
OESOPHAGUS	Establishment of RNA localization →	+0.115	+0.764	<.001	.002	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,991 associations by consensus.

Negative regulation of chromosome condensation by TNRC6B expression — KIDNEY

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