TNRC6A

Across TCGA patient cohorts, TNRC6A protein abundance is significantly associated with the RNA expression of many other genes, with 6,741 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TNRC6A-associated genes across cancer lineages are PIP5K1B, IKBIP, and GDF10. Each is linked with TNRC6A in more than 3 cancer types. Because this analysis shows association rather than direction, both TNRC6A-to-partner and partner-to-TNRC6A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNRC6A versus PIP5K1B in PDAC, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNRC6A→partner) and Y-score (partner→TNRC6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PIP5K1B →	-1.059	-0.453	.001	<.001	3	4
UCEC	IKBIP →	+0.590	+0.291	<.001	<.001	3	4
HNSC	GDF10 →	-0.925	-0.292	<.001	<.001	3	4
LSCC	PLCB4 →	-1.133	-0.196	.003	.002	3	3
HNSC	KLRB1 →	-0.706	-0.256	.001	<.001	3	3
LUAD	DSE →	+0.484	+0.223	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,741 associations by consensus.

TNRC6A vs PIP5K1B — PDAC

Explore this scatter interactively →