TNRC6A

Across TCGA cell cohorts, TNRC6A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,035 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TNRC6A-associated GO terms across cancer lineages are mRNA transport, Positive regulation of DNA metabolic process, and Nuclear export. Each is linked with TNRC6A in more than 17 cancer types. Because this analysis shows association rather than direction, both TNRC6A-to-partner and partner-to-TNRC6A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA transport grouped by TNRC6A-low versus TNRC6A-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNRC6A→partner) and Y-score (partner→TNRC6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	mRNA transport →	+0.148	+1.004	.003	<.001	3	18
BONE	Positive regulation of DNA metabolic process →	+0.073	+0.695	.002	.008	3	18
STOMACH	Nuclear export →	+0.107	+1.054	.001	.004	3	18
BREAST	Nuclear transport →	+0.088	+1.122	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Establishment of RNA localization →	+0.123	+1.401	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	RNA localization →	+0.107	+1.393	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,035 associations by consensus.

mRNA transport by TNRC6A expression — OESOPHAGUS

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