TNRC18

Across TCGA patient cohorts, TNRC18 protein abundance is significantly associated with the RNA expression of many other genes, with 8,711 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TNRC18-associated genes across cancer lineages are PMS2, BCL7A, and RFC5. Each is linked with TNRC18 in more than 3 cancer types. Because this analysis shows association rather than direction, both TNRC18-to-partner and partner-to-TNRC18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNRC18 versus PMS2 in HNSC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNRC18→partner) and Y-score (partner→TNRC18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PMS2 →	+0.497	+0.253	<.001	.001	3	4
GBM	BCL7A →	+0.527	+0.232	.002	.004	3	4
HNSC	RFC5 →	+0.631	+0.318	<.001	<.001	3	4
GBM	KLHL7 →	+0.576	+0.361	<.001	<.001	3	4
HNSC	FIGNL1 →	+0.666	+0.317	.001	<.001	3	4
HNSC	ZNF443 →	+0.758	+0.246	.001	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,711 associations by consensus.

TNRC18 vs PMS2 — HNSC

Explore this scatter interactively →