TNRC18

Across TCGA patient cohorts, TNRC18 mutation is significantly associated with the RNA expression of many other genes, with 4,267 significant associations in total. COAD shows the largest number of these associations.

The most reproducible TNRC18-associated genes across cancer lineages are RNA5SP477, TLCD3A, and B3GNT4. Each is linked with TNRC18 in more than 3 cancer types. Because this analysis shows association rather than direction, both TNRC18-to-partner and partner-to-TNRC18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP477 grouped by TNRC18-low versus TNRC18-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNRC18→partner) and Y-score (partner→TNRC18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RNA5SP477 →	+0.763	+3.750	<.001	<.001	3	4
COAD	TLCD3A →	+0.521	+2.938	<.001	<.001	3	4
COAD	B3GNT4 →	+0.464	+3.026	<.001	<.001	3	4
COAD	EPM2AIP1 →	-0.994	-4.060	<.001	<.001	3	4
COAD	GSR →	+0.529	+2.459	<.001	<.001	3	4
UCEC	ADAMTS8 →	-0.772	-1.613	.005	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,267 associations by consensus.

RNA5SP477 by TNRC18 expression — STAD

Explore this box plot interactively →