TNRC18

Across TCGA cell cohorts, TNRC18 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,408 significant associations in total. CNS shows the largest number of these associations.

The most reproducible TNRC18-associated GO terms across cancer lineages are Positive regulation of T-helper 17 cell lineage commitment, Regulation of miRNA metabolic process, and Positive regulation of intracellular steroid hormone receptor signaling pathway. Each is linked with TNRC18 in more than 14 cancer types. Because this analysis shows association rather than direction, both TNRC18-to-partner and partner-to-TNRC18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of T-helper 17 cell lineage commitment grouped by TNRC18-low versus TNRC18-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNRC18→partner) and Y-score (partner→TNRC18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of T-helper 17 cell lineage commitment →	+0.240	+1.361	.002	.002	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of miRNA metabolic process →	+0.090	+1.281	.001	<.001	3	15
OESOPHAGUS	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.178	+1.124	<.001	<.001	3	14
OESOPHAGUS	Cilium or flagellum-dependent cell motility →	-0.101	-1.108	<.001	<.001	3	13
OESOPHAGUS	Cilium-dependent cell motility →	-0.101	-1.108	<.001	<.001	3	13
OESOPHAGUS	Cilium movement involved in cell motility →	-0.108	-1.352	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,408 associations by consensus.

Positive regulation of T-helper 17 cell lineage commitment by TNRC18 expression — STOMACH

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