TNR

Across TCGA cell cohorts, TNR RNA expression is significantly associated with the go_rna of many other GO terms, with 292 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible TNR-associated GO terms across cancer lineages are Positive regulation of D-glucose transmembrane transport, Calcium-ion regulated exocytosis, and Regulation of clathrin coat assembly. Each is linked with TNR in more than 1 cancer types. Because this analysis shows association rather than direction, both TNR-to-partner and partner-to-TNR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of D-glucose transmembrane transport grouped by TNR-low versus TNR-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNR→partner) and Y-score (partner→TNR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of D-glucose transmembrane transport →	+0.078	+0.960	.001	.005	3	2
LUNG_SCLC	Calcium-ion regulated exocytosis →	+0.128	+0.976	.005	.003	3	2
LUNG_SCLC	Regulation of clathrin coat assembly →	+0.164	+0.844	<.001	<.001	3	2
LUNG_SCLC	Protein localization to perinuclear region of cytoplasm →	+0.103	+0.862	<.001	.007	3	2
LUNG_SCLC	Extraocular skeletal muscle development →	-0.097	-0.748	.003	.002	3	2
LUNG_SCLC	Negative regulation of transmembrane transport →	+0.055	+0.790	.002	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 292 associations by consensus.

Positive regulation of D-glucose transmembrane transport by TNR expression — LUNG_SCLC

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