TNPO3

Across TCGA patient cohorts, TNPO3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,988 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TNPO3-associated proteins across cancer lineages are PUS7, RBM28, and UBE2H. Each is linked with TNPO3 in more than 7 cancer types. Because this analysis shows association rather than direction, both TNPO3-to-partner and partner-to-TNPO3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNPO3 versus PUS7 in LSCC, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TNPO3→partner) and Y-score (partner→TNPO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PUS7 →	+0.514	+0.586	<.001	<.001	3	8
LSCC	RBM28 →	+0.436	+0.585	<.001	<.001	3	7
BRCA	UBE2H →	+0.419	+0.437	.002	<.001	3	7
LSCC	NUP205 →	+0.220	+0.521	<.001	<.001	3	7
LSCC	SSBP1 →	+0.590	+0.535	<.001	<.001	3	7
LSCC	CUL1 →	+0.332	+0.542	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,988 associations by consensus.

TNPO3 vs PUS7 — LSCC

Explore this scatter interactively →