TNP1

Across TCGA cell cohorts, TNP1 RNA expression is significantly associated with the mutation status of many other genes, with 193 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TNP1-associated genes across cancer lineages are HIF1A, THOC5, and MAGI2. Each is linked with TNP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TNP1-to-partner and partner-to-TNP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HIF1A grouped by TNP1-low versus TNP1-high in BLOOD_Leukemia.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNP1→partner) and Y-score (partner→TNP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	HIF1A →	+3.984	+0.083	.006	<.001	3	3
SOFT_TISSUE	THOC5 →	+5.369	+1.481	.004	<.001	3	2
SOFT_TISSUE	MAGI2 →	+4.369	+1.110	.008	<.001	3	2
SOFT_TISSUE	RIF1 →	+4.369	+1.110	.008	<.001	3	2
SOFT_TISSUE	MYO15A →	+3.369	+0.506	.001	.007	3	2
LARGE_INTESTINE	EPS8L3 →	+4.415	+0.160	.007	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 193 associations by consensus.

HIF1A by TNP1 expression — BLOOD_Leukemia

Explore this box plot interactively →