TNP1

Across TCGA pan-cancer cohorts, TNP1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of TNP1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where TNP1 RNA is repressed in tumor relative to normal tissue. In most cancer types TNP1 is over-expressed in tumor, although a few such as THCA and ESCA show the opposite, repressed pattern.

THCA, ESCA, and KIRC are the cancer types where TNP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TNP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	All	−1.258	<.001	9	view →
ESCA	Male	All	−0.092	.041	1	view →
KIRC	All	All	−0.019	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

TNP1–THCA

Open the THCA breakdown →