TNNT3

Across TCGA patient cohorts, TNNT3 protein abundance is significantly associated with the RNA expression of many other genes, with 8,536 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TNNT3-associated genes across cancer lineages are KRT18P34, PRUNE2, and LINC02466. Each is linked with TNNT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNNT3-to-partner and partner-to-TNNT3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNNT3 versus KRT18P34 in HNSC, with a Pearson correlation of -0.19.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNNT3→partner) and Y-score (partner→TNNT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	KRT18P34 →	-0.527	-0.802	<.001	<.001	3	2
HNSC	PRUNE2 →	+1.497	+1.108	<.001	<.001	3	2
HNSC	LINC02466 →	-1.103	-1.054	<.001	<.001	3	2
HNSC	LINC02428 →	-1.194	-1.180	<.001	<.001	3	2
OV	RPS6KA2 →	+0.603	+0.685	<.001	.005	3	2
LUAD	BIK →	+0.975	+0.441	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,536 associations by consensus.

TNNT3 vs KRT18P34 — HNSC

Explore this scatter interactively →