TNNT2

Across TCGA patient cohorts, TNNT2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,553 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TNNT2-associated genes across cancer lineages are CYTH4, ETV7, and NCF4. Each is linked with TNNT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNNT2-to-partner and partner-to-TNNT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNNT2 versus CYTH4 in HNSC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNNT2→partner) and Y-score (partner→TNNT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CYTH4 →	+0.772	+0.682	.004	<.001	3	1
HNSC	ETV7 →	+0.776	+0.502	.005	.003	3	1
HNSC	NCF4 →	+0.920	+0.604	.008	.005	3	1
HNSC	GZMH →	+1.089	+0.586	.009	.003	3	1
HNSC	GZMB →	+1.607	+0.754	<.001	.005	3	1
HNSC	ASB2 →	+1.099	+0.699	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,553 associations by consensus.

TNNT2 vs CYTH4 — HNSC

Explore this scatter interactively →